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The Application Of Sulfobutyl Ether Beta Cyclodextrin Sodium

The Application of Sulfobutyl Ether Beta Cyclodextrin Sodium

Sulfobutyl Ether Beta Cyclodextrin Sodium(SBECD) is a new type of anionic high soluble cyclodextrin derivatives. It could include drug molecules to from covalent compounds so that increase the drug’s solubility, stability, safety. It could reduce the renal toxicity, moderate drug’s hemolysis, control the release rate and cover up the bad smell. 

It can be used as a solubilizer, wetting agent, chelating agent (complexing agent) and polyvatent masking agent. It has been used in injection, oral, nasal and eye medicines. It has a special affinity and inclusion for nitrogen drugs.

 

In injection formulation:

Function: solubilizer, stabilizer. Increase the solubility and stability of insoluble drugs, develop them into injection formulation easier.

Eg: SBECD could increase the solibility of Docetaxel, Voriconazole, Ibuprofen, Indomethacin etc. It could increase the stability of Carmustine etc.

 磺丁基应用1.jpg

In oral formulation:

Function: solubilizer, stabilizer. Increase the bioavailability of insoluble drugs.

Eg: SBECD could increase the bioavailability of Flunarizine, Danazol, Hydroprednisone, Prasugrel etc.

 

In ophthalmic preparation:

Function: solubilizer, stabilizer. Decrease drug stimulation.

Eg: SBECD could decrease the stimulant of Pilocarpine, Dipivefrine, Balofloxacin, Acyclovir etc.

 

In nasal preparation:

Function: solubilizer, stabilizer. Increase the permeability of the nasal mucosa, increase the solubility and stability of drugs, and improve the metabolic rate of the drug delivery target.

Eg: SBECD could increase the solibility and stability of Midazolam etc.

磺丁基应用2.jpg

In ointments:

Function: solubilizer, stabilizer. Increase the solubility and stability of drugs.

Eg: SBECD could increase the solibility and stability of Nimesulide etc.

 

SBECD is a newly researched and developed strong product of our company. Any demand of SBECD, please feel free to contact us ! Qianhui - Leader of Cyclodextrin Tel: +86 533 3780067   Web: www.cyclodextrinchina.com


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